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Background: Glucose meter analytical demeanour criteria required for safe and actual administration of patients on densely glycemic control (TGC) are not currently defined. We used simulation modeling to couple glucose meter performance characteristics to insulin dosing errors during TGC.

Methods: We acclimatized 29 920 glucose values from patients on TGC at 1 formation to imitate the expected distribution of glucose values during TGC, and we against 2 different simulation models to apply to glucose meter analytical dispatch to insulin dosing gaffe using these 29 920 approve glucose values and assuming 10%, 15%, or 20% full allowable slip (TEa) criteria.

Results: One-category insulin dosing errors were joint below all boob conditions. Two-category insulin dosing errors occurred more again when either 20% or 15% TEa was assumed compared with 10% thorough boo-boo. Dosing errors of 3 or more categories, those most likely to upshot in hypoglycemia and in this manner lenient harm, occurred seldom out of sight all literal conditions with the umbrage at of 20% TEa.

Conclusions: Glucose meter technologies that carry on within a 15% comprehensive allowable misprint tolerance are remote to produce in a body (≥3-category) insulin dosing errors during TGC. Increasing performance to 10% TEa should diet the frequency of 2-category insulin dosing errors, although additional studies are of the utmost importance to affect the clinical contact of such errors during TGC. Widely known criteria that consideration 20% total allowable bloomer in glucose meters may not be optimal for case administration during TGC.