Archive for the ‘Laboratory Management’ Category
Should I Repeat My 1:2s QC Rejection? [Laboratory Management]
Written by Parvin, C. A., Kuchipudi, L., Yundt-Pacheco, J. C. on April 27, 2012 – 7:01 pm -Repeating a QC that is outside 2SD from the mean (1:2s rule) appears to be a common practice. Although this form of repeat sampling is frowned on by many, the comparative power of the approach has not been formally evaluated.
METHODS:We computed power functions mathematically and by computer simulation for 4 different 1:2s repeat-sampling strategies, as well as the 1:2s rule, the 1:3s rule, and 2 common QC multirules.
RESULTS:The false-rejection rates for the repeat-sampling strategies were similarly low to those of the 1:3s QC rule. The error detection rates for the repeat-sampling strategies approached those of the 1:2s QC rule for moderate to large out-of-control error conditions. In most cases, the power of the repeat-sampling strategies was superior to the power of the QC multirules we evaluated. The increase in QC utilization rate ranged from 4% to 13% for the repeat-sampling strategies investigated.
CONCLUSIONS:The repeat-sampling strategies provide an effective tactic to take advantage of the desirable properties of both the 1:2s and 1:3s QC rules. Additionally, the power of the repeat-sampling strategies compares favorably with the power of 2 common QC multirules. These improvements come with a modest increase in the average number of controls tested.
Tags: chemistry, clinic
Posted in Clinical Chemistry, Laboratory Management | Comments Off
Deprecating Communication [Editorials] <<>>
Written by Valenstein, P. on January 1, 1970 – 1:00 am -Tags: chemistry, clinic
Posted in Clinical Chemistry, Laboratory Management | Comments Off
Fiendish Sensible reciprocity Glucose Standards [Letters to the Editor] <<>>
Written by Krouwer, J. S. on January 1, 1970 – 1:00 am -Tags: chemistry, clinic
Posted in Clinical Chemistry, Laboratory Management | Comments Off
